A new survey completed Oct. 17 shows Democrat Claire McCaskill with a double-digit lead over Republican Todd Akin in Missouri’s pivotal U.S. Senate campaign.

This is a race that speaks volumes about the Republicans’ misfortunes and unfavorable tide trending against their hopes for pickups in the 2012 U.S. Senate race, according to Harstad Strategic Research, Inc.

In a three-way race also including Libertarian candidate Jonathan Dine, McCaskill holds a 12-point lead and gets more vote than the two men combined: 47 percent for McCaskill, 35 percent for Akin and 8 percent for Dine, with just 8 percent undecided.

In a two-way race excluding the Libertarian, McCaskill holds a 10-point lead and gets 50 percent of the vote to Akin’s 40 percent.